M210. GRIN2B METHYLATION IS RELATED TO PANSS EXCITED COMPONENT (PANSS-EC) IN SCHIZOPHRENIA
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چکیده
منابع مشابه
Response to inhaled loxapine in patients with schizophrenia or bipolar I disorder: PANSS-EC responder analyses
Background Efficacy of inhaled loxapine 5 or 10 mg in treating agitation was shown using the Positive and Negative Syndrome Scale - Excited Component (PANSS-EC) in two Phase III randomised, double-blind, placebo-controlled trials in 344 agitated patients with schizophrenia and 314 patients with bipolar I disorder (Clinicaltrials.gov: NCT00628589, NCT00721955). Aims To examine the five individ...
متن کاملThe positive and negative syndrome scale (PANSS) for schizophrenia.
The variable results of positive-negative research with schizophrenics underscore the importance of well-characterized, standardized measurement techniques. We report on the development and initial standardization of the Positive and Negative Syndrome Scale (PANSS) for typological and dimensional assessment. Based on two established psychiatric rating systems, the 30-item PANSS was conceived as...
متن کاملThe PANSS should be rescaled.
Obermeier and colleagues address an at-first glance trivial issue, which, however, has major implications on the analysis and interpretation of clinical trials: The scaling of the Positive and Negative Syndrome Scale (PANSS). The original version of the scale uses a 1–7 rating system that creates major problems of interpretation when it comes to the calculation of responder rates based on perce...
متن کاملShould the PANSS be rescaled?
The design of the Positive and Negative Syndrome Scale (PANSS) with item levels ranging from 1 to 7 leads to the trivial result that the 30-item scale's zero level (no symptoms) is 30. This causes serious problems when ratios are calculated which always implicitly depend on a natural zero point (equals 0). Recent publications concerning efficacy of antipsychotics correctly suggest a subtraction...
متن کاملIs the PANSS used correctly? a systematic review
BACKGROUND The PANSS (Positive and Negative Syndrome Scale) is one of the most important rating instruments for patients with schizophrenia. Nevertheless, there is a long and ongoing debate in the psychiatric community regarding its mathematical properties.All 30 items range from 1 to 7 leading to a minimum total score of 30, implying that the PANSS is an interval scale. For such interval scale...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2020
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sbaa030.522